Stay in the heart of Syracuse – This neighborhood is a great choice for travelers interested in atmosphere, restaurants and architecture – Check location Excellent location – show map One of our top picks in Syracuse.Located in Siracusa in the Sicily region, Casa Ortigia is a apartment featuring free WiFi. This apartment features a terrace. Syracuse Cathedral is 1,300 feet from the apartment, while Porto Piccolo is a 9-minute walk from the property. The nearest airport is Catania Fontanarossa Airport, 39 mi from Casa Ortigia. Ortigia is a great choice for travelers interested in atmosphere, restaurants and architecture.